Nitric oxide, peripheral vascular resistance and cardiac output during normal pregnancy in adolescents

Inhaled nitric oxide in patients with normal and increased pulmonary vascular resistance after cardiac surgery.

We studied the haemodynamic effects of inhaled nitric oxide 40 p.p.m. in two groups of patients after cardiac surgery (mitral valve surgery or coronary artery bypass grafting). Nitric oxide caused a significant reduction in pulmonary vascular resistance after mitral valve surgery in patients who had pre-existing pulmonary hypertension, but no change in haemodynamic state in the coronary artery ...

P-183: TGF-? Level and Insulin Resistance during Normal Pregnancy

Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance.

OBJECTIVE Obesity causes inflammation and insulin resistance in the vasculature as well as in tissues involved in glucose metabolism such as liver, muscle, and adipose tissue. To investigate the relative susceptibility of vascular tissue to these effects, we determined the time course over which inflammation and insulin resistance develops in various tissues of mice with diet-induced obesity (D...

Cardiac Output, and Vascular Resistance in Cardiac Transplant Recipients

Background An attenuated or absent nocturnal decline in blood pressure has repeatedly been documented in cardiac transplant recipients. The present study was aimed at investigating the hemodynamic mechanism underlying this abnormality. Methods and Results In 23 cardiac transplant recipients (11 to 36 months after transplantation) and in 23 control subjects matched for age and 24-hour mean arter...

Interrelationships of cardiac output, blood pressure, and peripheral resistance during normal respiration in normotensive and hypertensive individuals.

The effects of normal respiration upon the heart, blood pressure, and peripheral circulation were studied in normotensive and hypertensive subjects. Changes of right and left ventricular output were measured by the ballistocardiogram and the pressure-pulse method of Remington, peripheral blood flow by plethysmographs. The central and peripheral changes were interrelated and evidence is presente...